Thursday, March 11, 2010

A vision for personalized medicine

Genomics Pioneer Leroy Hood says a coming revolution in medicine will bring enormous new opportunities:-

1-Leroy Hood had been at the center of a number of paradign shifts in biology. He helped in invent the first automated DNA sequencing machine in the 1980s along with several other technologies that have changed the face of molecular biology.
2-In 2000 he founded the Institute of Systems Biology, Seattle. Dedicated to examining the interactions between biological information at many different levesl and to moving forward a new perspective for studying biology.
3-He has founded a startup called Integrated Diagnostics to develop cheap diagnostics  that could be used to detect diseases at earlier more treatable stages.
4- He developed partnership between the institute of Systems Biology and Ohio State Medical School  to combine existing medical and genomics techonlogies can affect the practice of health care today.
 5- According to him, the personalized medicine  may be defined as P4 medicine- Powerfully predictive, Personalized, Preventative- meaning we shall shift the focus to wellness and Participatory.
6- Nanotechnology approaches to protein measurement- measuring 2,500 proteins from a drop of blood will also be important. We want to develop tests to asses 50 organ specific protein from 50 organs as way of interrogating health rather than disease.
7-We can analyze transcriptome and RNAomes, Proteomes and Metabolomes( the collection of transcribed genes or mRNA, Total RNA, Proteins and Metabolites respectively in the cell). That information will reveal quanti cellular states that will say lots about normal mechanisms and disease mechanisms.
8-Computational and Mathematical tools to deal with data dimensionality.

Credit to Technology Review

No comments:

Post a Comment