Massimo Filippi & Maria A. Rocca
Abstract
Multiple sclerosis (MS) is a chronic, inflammatory, demyelinating disease that mainly affects young adults, and is characterized by heterogeneous clinical manifestations, biological and surrogate markers of which might be used to monitor disease evolution using immunological, genetic and MRI measures.Since the early 1990s, the introduction of disease-modifying treatments (DMTs) has notably changed the progression of MS.
Nature Reviews Neurology 6, 421-422 (August 2010) | doi:10.1038/nrneurol.2010.88
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