Apoptosis and the subsequent clearance
of dying cells occurs throughout
development and adult life in many
tissues. Failure to promptly clear
apoptotic cells has been linked to many
diseases1, 2, 3. ELMO1 is an evolutionarily
conserved cytoplasmic engulfment
protein that functions downstream of the
phosphatidylserine receptor BAI1, and,
along with DOCK1 and the GTPase RAC1,
Nature 467, 333-337 (16 September 2010) |
doi:10.1038/nature09356; Received 24 March 2010; Accepted 12 July
2010
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