The nucleotide sequence of pNL194, a VIM-1-encoding plasmid, is described in this study. pNL194 (79,307 bp) comprised an IncN-characteristic segment (38,940 bp) and a mosaic structure (40,367 bp) including blaVIM-1, aacA7, aadA1, aadA2, dfrA1, dfrA12, aphA1, strA, strB, and sul1. Tn1000 or Tn5501 insertion within fipA probably facilitated recruitment of additional mobile elements carrying resistance genes.
Antimicrobial Agents and Chemotherapy, October 2010, p. 4497-4502, Vol. 54, No. 10
0066-4804/10/$12.00+0 doi:10.1128/AAC.00665-1
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